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Struggling with Weight Gain After 40? Read this!

  • Writer: Jaime Heer, FNTP
    Jaime Heer, FNTP
  • Mar 31
  • 3 min read

Understanding the Root Causes & Effective Strategies for a Healthy Metabolism after 40


Weight gain after 40

Perimenopause typically begins around age 40 and can last at least 10 years, bringing a host of unwelcome changes—including weight gain. Even those who have maintained a steady weight for years may suddenly find themselves gaining pounds, particularly around the midsection. But why does this happen? And more importantly, what can you do about it? At Origins Integrative Medicine, we believe in getting to the root causes and providing effective, science-backed solutions.


Why Does Weight Gain Happen in Perimenopause?

Several physiological shifts contribute to weight gain during this stage of life, including:


1. Cortisol Dysregulation

As estrogen levels fluctuate, the body's stress response can become more erratic. Perimenopausal women often experience increased cortisol levels due to poor sleep, life stressors, and hormonal imbalances. Chronically high cortisol promotes fat storage, particularly in the abdominal area, and contributes to blood sugar imbalances, muscle loss, and increased cravings for refined carbohydrates.


2. Changes in Insulin Sensitivity

With age and hormonal changes, insulin sensitivity tends to decline, making the body less efficient at processing carbohydrates. This means that foods that were once tolerated well may now lead to blood sugar spikes, followed by crashes that promote cravings and fat storage. Insulin resistance also increases inflammation, making it harder to lose weight.


3. Changes in Estrogen Levels

Estrogen fluctuations in perimenopause can significantly impact metabolism. As estrogen levels rise and fall unpredictably, women may experience changes in fat distribution, increased fat storage in the midsection, and difficulty maintaining muscle mass. These hormonal shifts can also influence energy levels and appetite regulation, making weight management more challenging.


4. Poor Detoxification

The body's ability to detoxify estrogen and other metabolic byproducts efficiently can decline during perimenopause, leading to a buildup of toxins that may contribute to weight gain, inflammation, and hormonal imbalances. Supporting detox pathways through diet and lifestyle can help maintain a healthy metabolism.


How to Combat Perimenopausal Weight Gain

While these metabolic changes may seem frustrating, the good news is that you can take proactive steps to maintain a healthy weight and feel your best.

stuffed avocado

1. Eat an Anti-Inflammatory, Protein-Rich Diet

What you eat plays a crucial role in managing perimenopausal weight gain. An anti-inflammatory diet rich in high-quality protein helps stabilize blood sugar, balance hormones, and support muscle maintenance. Consider these dietary strategies:

  • Prioritize Protein: Aim for 20-30 grams of protein per meal from sources like wild-caught fish, grass-fed & finished meats, pasture-raised poultry and eggs and sprouted, nuts, seeds and legumes.

  • Choose Healthy Fats: Include anti-inflammatory fats from sources like avocados, olive oil, nuts, seeds and wild salmon to support hormone production and satiety.

  • Limit Processed Carbs and Sugars: Reducing refined sugars and processed foods can help stabilize blood sugar levels and reduce inflammation.

  • Increase Fiber Intake: Fiber from vegetables, nuts, and seeds helps support gut health and estrogen detoxification.


2. Manage Stress and Support Sleep

Since stress and poor sleep contribute to weight gain, prioritizing stress management is essential.

  • Practice Relaxation Techniques: Meditation, deep breathing, and restorative yoga can help lower cortisol levels.

  • Get Quality Sleep: Aim for 7-9 hours of restorative sleep per night. Optimize your sleep environment by reducing blue light exposure before bed, keeping the room cool, using breathable & organic cotton sheet & sleep wear while also maintaining a consistent sleep schedule.

  • Support Adrenal Health: Adaptogenic herbs like ashwagandha and Rhodiola may help balance the stress response and support energy levels.


3. Prioritize Strength Training

One of the best ways to counteract muscle loss and metabolic slowdowns is by incorporating weight training into your routine. Strength training helps:

  • Preserve and build lean muscle mass, which increases metabolic rate.

  • Improve insulin sensitivity, making it easier to process carbohydrates efficiently.

  • Reduce cortisol levels by promoting a balanced stress response. Aim for at least 2-3 days of strength training per week, focusing on compound movements like squats, deadlifts, and push-ups to build functional strength.


Perimenopausal weight gain isn’t inevitable, nor is it a sign of failure. By addressing the underlying causes—cortisol dysregulation, insulin resistance, detoxification and hormone balance—you can take control of your health. Strength training, an anti-inflammatory diet rich in high-quality protein, prioritizing sleep and stress management are powerful tools to maintain a healthy weight and feel your best during this transition.

Dr. Evans Naturopathic Doctor

At Origins Integrative Medicine, we specialize in holistic, personalized approaches to hormonal health. If you’re struggling with weight gain or other perimenopausal symptoms, our team is here to help you navigate this phase with confidence and vitality. Schedule a consultation today to get started on your wellness journey!



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